Best local LLMs for the AMD Instinct MI325X

Each list assumes the context that task needs, so a model that fits for chat may rank lower for long documents.

General chat at 8K context

  1. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. DeepSeek V4 Flash (284B-A13B) Q5_K_M · 167 tok/s · Runs well (tight fit)
  2. 93Excellent quality (A+) · 93 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. GLM-5.3 Flash (320B-A18B) Q5_K_M · 144 tok/s · Runs well (tight fit)
  3. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. Hunyuan Hy3 (295B-A21B) Q5_K_M · 133 tok/s · Runs well (tight fit)
  4. 92Excellent quality (A+) · 92 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. Inkling Small (276B-A12B) Q6_K · 158 tok/s · Runs well (tight fit)
  5. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. MiMo V2.5 (310B-A15B) Q5_K_M · 157 tok/s · Runs well (tight fit)

Coding at 32K context

  1. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. DeepSeek V4 Flash (284B-A13B) Q5_K_M · 167 tok/s · Runs well (tight fit)
  2. 93Excellent quality (A+) · 93 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. GLM-5.3 Flash (320B-A18B) Q5_K_M · 144 tok/s · Runs well (tight fit)
  3. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. Hunyuan Hy3 (295B-A21B) Q5_K_M · 133 tok/s · Runs well (tight fit)
  4. 92Excellent quality (A+) · 92 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. Inkling Small (276B-A12B) Q6_K · 158 tok/s · Runs well (tight fit)
  5. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. MiMo V2.5 (310B-A15B) Q5_K_M · 157 tok/s · Runs well (tight fit)

Reasoning at 32K context

  1. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. DeepSeek V4 Flash (284B-A13B) Q5_K_M · 167 tok/s · Runs well (tight fit)
  2. 93Excellent quality (A+) · 93 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. GLM-5.3 Flash (320B-A18B) Q5_K_M · 144 tok/s · Runs well (tight fit)
  3. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. Hunyuan Hy3 (295B-A21B) Q5_K_M · 133 tok/s · Runs well (tight fit)
  4. 92Excellent quality (A+) · 92 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. Inkling Small (276B-A12B) Q6_K · 158 tok/s · Runs well (tight fit)
  5. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. MiMo V2.5 (310B-A15B) Q5_K_M · 157 tok/s · Runs well (tight fit)

Documents (RAG) at 32K context

  1. 93Excellent quality (A+) · 93 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. GLM-5.3 Flash (320B-A18B) Q5_K_M · 144 tok/s · Runs well (tight fit)
  2. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. Hunyuan Hy3 (295B-A21B) Q5_K_M · 133 tok/s · Runs well (tight fit)
  3. 92Excellent quality (A+) · 92 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. Inkling Small (276B-A12B) Q6_K · 158 tok/s · Runs well (tight fit)
  4. 93Excellent quality (A+) · 93 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. MiMo V2.6 Flash (310B-A15B) Q5_K_M · 157 tok/s · Runs well (tight fit)
  5. 90Excellent quality (A+) · 90 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. MiniMax M2.1 (230B-A10B) Q6_K · 170 tok/s · Runs great

Agents & tools at 64K context

  1. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. DeepSeek V4 Flash (284B-A13B) Q5_K_M · 167 tok/s · Runs well (tight fit)
  2. 93Excellent quality (A+) · 93 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. GLM-5.3 Flash (320B-A18B) Q5_K_M · 144 tok/s · Runs well (tight fit)
  3. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. Hunyuan Hy3 (295B-A21B) Q5_K_M · 133 tok/s · Runs well (tight fit)
  4. 92Excellent quality (A+) · 92 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. Inkling Small (276B-A12B) Q6_K · 158 tok/s · Runs well (tight fit)
  5. 91Excellent quality (A+) · 91 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 100/100 (quality, fit, speed and memory use) sets the ranking. MiMo V2.5 (310B-A15B) Q5_K_M · 157 tok/s · Runs well (tight fit)

Reverse engineering at 32K context

  1. 96Excellent quality (A+) · 96 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 98/100 (quality, fit, speed and memory use) sets the ranking. Qwen3.8 Flash Next (125B-A6B) Q8_0 · 177 tok/s · Runs great
  2. 92Excellent quality (A+) · 92 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 96/100 (quality, fit, speed and memory use) sets the ranking. MiniMax M2.7 (230B-A10B) Q6_K · 170 tok/s · Runs great
  3. 92Excellent quality (A+) · 92 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 96/100 (quality, fit, speed and memory use) sets the ranking. Step 3.7 Flash (198B-A11B) Q6_K · 164 tok/s · Runs great
  4. 92Excellent quality (A+) · 92 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 96/100 (quality, fit, speed and memory use) sets the ranking. Nex N2.6 (321B-A18B) Q4_K_M · 161 tok/s · Runs great
  5. 92Excellent quality (A+) · 92 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 96/100 (quality, fit, speed and memory use) sets the ranking. GLM-5.3 Flash (320B-A18B) Q4_K_M · 161 tok/s · Runs great

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.

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