Laguna S 2.1 (118B-A8B) on AMD Ryzen AI Max+ 395 (64 GB)

Can the AMD Ryzen AI Max+ 395 (64 GB) run Laguna S 2.1 (118B-A8B)?

Yes, but slowly (far over GPU memory limit)

Slow (far over GPU memory limit). At Q2_K it needs about 53.1 GB of 48.0 GB usable, with an estimated speed of 40.2 tok/s.

Best quant: Q2_K
Generation speed: 40.2 tok/s
Prompt processing: 4,604 tok/s
First token (1K prompt): 0.3 s
Largest safe context: —

Best app to run it on the AMD Ryzen AI Max+ 395 (64 GB)

On Windows

Lemonade

Desktop app · runs on llama.cpp, ONNX Runtime GenAI (Ryzen AI NPU)

Splits the model between GPU memory and system RAM, which this setup needs.
Built for Ryzen AI and Strix Halo, including NPU + iGPU modes on Windows.

lemonade pull poolside/Laguna-S-2.1-GGUF:Q2_K

llama.cpp Splits the model between GPU memory and system RAM, which this setup needs.
LM Studio Splits the model between GPU memory and system RAM, which this setup needs.

On Linux

Lemonade

Desktop app · runs on llama.cpp, ONNX Runtime GenAI (Ryzen AI NPU)

Splits the model between GPU memory and system RAM, which this setup needs.
Built for Ryzen AI and Strix Halo, including NPU + iGPU modes on Windows.

lemonade pull poolside/Laguna-S-2.1-GGUF:Q2_K

llama.cpp Splits the model between GPU memory and system RAM, which this setup needs.
LM Studio Splits the model between GPU memory and system RAM, which this setup needs.

Want an agent? Laguna S 2.1 (118B-A8B) supports tool use, so you can pair a llama.cpp or MLX LM server with one of these. Apps that run on this computer come first.

Coding agents

Personal assistants

How we choose: the files published for this model, your operating system and GPU, whether it fits fully in memory, and published speed tests (MLX vs llama.cpp on Apple silicon, vLLM vs llama.cpp vs Ollama on NVIDIA). Details.

Download Laguna S 2.1 (118B-A8B)

Quantized files · GGUF

Works in LM Studio, llama.cpp, Jan and Ollama. No sign-in needed.

huggingface.co/poolside/Laguna-S-2.1-GGUF (opens in a new tab)

ollama run hf.co/poolside/Laguna-S-2.1-GGUF

Original weights · Hugging Face

Full-precision files from Poolside, for fine-tuning, vLLM, Transformers.

huggingface.co/poolside/Laguna-S-2.1 (opens in a new tab)

No sign-in needed.

Links checked 3 days ago against Hugging Face, Ollama and GitHub.

How it’s rated

Quality 60Good quality (B) · 60 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 61/100 (quality, fit, speed and memory use) sets the ranking.: How capable the model itself is at Q2_K, from its editorial quality tier scaled by the quantization or precision. It’s the same on any hardware that runs this variant. Scale: A+ 85+ · A 70+ · B 55+ · C 40+ · D under 40.
Runs Slowfar over GPU memory limit: How well it runs on the AMD Ryzen AI Max+ 395 (64 GB): speed, capped by how well it fits in memory. Runs great: 30+ tokens/s (or near the image, video or decision speed target) · Runs well: 10+ tokens/s · Slow: 3+ tokens/s · Very slow: under 3 · Won’t run: doesn’t fit even with offload. A tight fit or RAM offload caps it at Runs well; heavy offload caps it at Slow.

Match score

To order lists, each result also gets a match score out of 100 from four parts. It favors the most capable model that still runs well.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.	27.1 / 45
Memory fitFull marks when the model fits in the share of unified memory the GPU can use; fewer when it goes past that limit.	4.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.	15.0 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.	15.0 / 15
Match score	61.1 / 100

The match score orders results; it is not shown as a grade. Quality and Runs are the two ratings in the tables.

Every quantization on the AMD Ryzen AI Max+ 395 (64 GB)

Quant	Memory needed	Available	Speed	Runs	Quality	Download
`Q2_K`	53.1 GB	48.0 GB	40.2 tok/s	Slowfar over GPU memory limit	60Good quality (B) · 60 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 61/100 (quality, fit, speed and memory use) sets the ranking.	GGUF files (opens in a new tab)
`Q3_K_M`	63.7 GB	48.0 GB	—	Won't run	72Great quality (A) · 72 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking.	GGUF files (opens in a new tab)
`Q4_K_M`	77.8 GB	48.0 GB	—	Won't run	81Great quality (A) · 81 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 11/100 (quality, fit, speed and memory use) sets the ranking.	GGUF (opens in a new tab)
`Q5_K_M`	89.5 GB	48.0 GB	—	Won't run	83Great quality (A) · 83 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 11/100 (quality, fit, speed and memory use) sets the ranking.	GGUF files (opens in a new tab)
`Q6_K`	102 GB	48.0 GB	—	Won't run	85Excellent quality (A+) · 85 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 11/100 (quality, fit, speed and memory use) sets the ranking.	GGUF files (opens in a new tab)
`Q8_0`	131 GB	48.0 GB	—	Won't run	86Excellent quality (A+) · 86 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 11/100 (quality, fit, speed and memory use) sets the ranking.	GGUF (opens in a new tab)
`F16`	241 GB	48.0 GB	—	Won't run	86Excellent quality (A+) · 86 of 100: how capable the model is at F16, whatever it runs on. Match score 11/100 (quality, fit, speed and memory use) sets the ranking.	GGUF (opens in a new tab) Original weights (opens in a new tab)

Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.

Other hardware that runs it

86Excellent quality (A+) · 86 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 93/100 (quality, fit, speed and memory use) sets the ranking. Apple M3 Ultra (256 GB) Q8_0 · 45.5 tok/s · Runs great
85Excellent quality (A+) · 85 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 93/100 (quality, fit, speed and memory use) sets the ranking. Apple M2 Ultra (192 GB) Q6_K · 58.0 tok/s · Runs great
81Great quality (A) · 81 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 91/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA RTX PRO 6000 Blackwell Q4_K_M · 143 tok/s · Runs great
81Great quality (A) · 81 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 91/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA RTX Spark N1X (6144-core GPU) (128 GB) Q4_K_M · 39.9 tok/s · Runs great
83Great quality (A) · 83 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 91/100 (quality, fit, speed and memory use) sets the ranking. Apple M4 Max (128 GB) Q5_K_M · 49.3 tok/s · Runs well (tight fit)
81Great quality (A) · 81 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 91/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA GB10 (128 GB) Q4_K_M · 36.7 tok/s · Runs great

Quick answers

How much memory does Laguna S 2.1 (118B-A8B) need on the AMD Ryzen AI Max+ 395 64GB?

At Q2_K it needs about 53.1 GB. The AMD Ryzen AI Max+ 395 64GB has 48.0 GB usable.

How fast is Laguna S 2.1 (118B-A8B) on the AMD Ryzen AI Max+ 395 64GB?

About 40.2 tok/s at Q2_K, an estimate from the hardware’s memory bandwidth and the size of the model.

Which quantization of Laguna S 2.1 (118B-A8B) should I use on the AMD Ryzen AI Max+ 395 64GB?

Q2_K. Of the versions that fit, it is the one that runs best; when two run equally well, the check prefers the higher-rated one.

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.