Laguna XS 2.1 (33B-A3B) on AMD Ryzen AI Max 385 (64 GB)

Can the AMD Ryzen AI Max 385 (64 GB) run Laguna XS 2.1 (33B-A3B)?

Yes, it runs great

Runs great. At Q6_K it needs about 33.2 GB of 48.0 GB usable, with an estimated speed of 51.1 tok/s.

Best quant: Q6_K
Generation speed: 51.1 tok/s
Prompt processing: 9,486 tok/s
First token (1K prompt): 0.3 s
Largest safe context: 96K

Best app to run it on the AMD Ryzen AI Max 385 (64 GB)

On Windows

Lemonade

Desktop app · runs on llama.cpp, ONNX Runtime GenAI (Ryzen AI NPU)

Built for Ryzen AI and Strix Halo, including NPU + iGPU modes on Windows.

lemonade pull poolside/Laguna-XS-2.1-GGUF:Q6_K

LM Studio Point-and-click: search, download and chat in one window.
llama.cpp Usually the first to support new model architectures.

On Linux

Lemonade

Desktop app · runs on llama.cpp, ONNX Runtime GenAI (Ryzen AI NPU)

Built for Ryzen AI and Strix Halo, including NPU + iGPU modes on Windows.

lemonade pull poolside/Laguna-XS-2.1-GGUF:Q6_K

LM Studio Point-and-click: search, download and chat in one window.
llama.cpp Usually the first to support new model architectures.

How we choose: the files published for this model, your operating system and GPU, whether it fits fully in memory, and published speed tests (MLX vs llama.cpp on Apple silicon, vLLM vs llama.cpp vs Ollama on NVIDIA). Details.

Download Laguna XS 2.1 (33B-A3B)

Quantized files · GGUF

Works in LM Studio, llama.cpp, Jan and Ollama. No sign-in needed.

huggingface.co/poolside/Laguna-XS-2.1-GGUF (opens in a new tab)

ollama run hf.co/poolside/Laguna-XS-2.1-GGUF

Original weights · Hugging Face

Full-precision files from Poolside, for fine-tuning, vLLM, Transformers.

huggingface.co/poolside/Laguna-XS-2.1 (opens in a new tab)

No sign-in needed.

Links checked 3 days ago against Hugging Face, Ollama and GitHub.

How it’s rated

Quality 81Great quality (A) · 81 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 91/100 (quality, fit, speed and memory use) sets the ranking.: How capable the model itself is at Q6_K, from its editorial quality tier scaled by the quantization or precision. It’s the same on any hardware that runs this variant. Scale: A+ 85+ · A 70+ · B 55+ · C 40+ · D under 40.
Runs Runs great: How well it runs on the AMD Ryzen AI Max 385 (64 GB): speed, capped by how well it fits in memory. Runs great: 30+ tokens/s (or near the image, video or decision speed target) · Runs well: 10+ tokens/s · Slow: 3+ tokens/s · Very slow: under 3 · Won’t run: doesn’t fit even with offload. A tight fit or RAM offload caps it at Runs well; heavy offload caps it at Slow.

Match score

To order lists, each result also gets a match score out of 100 from four parts. It favors the most capable model that still runs well.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.	36.5 / 45
Memory fitFull marks when the model fits in the share of unified memory the GPU can use; fewer when it goes past that limit.	25.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.	15.0 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.	15.0 / 15
Match score	91.5 / 100

The match score orders results; it is not shown as a grade. Quality and Runs are the two ratings in the tables.

Every quantization on the AMD Ryzen AI Max 385 (64 GB)

Quant	Memory needed	Available	Speed	Runs	Quality	Download
`Q2_K`	19.2 GB	48.0 GB	101 tok/s	Runs great	57Good quality (B) · 57 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 75/100 (quality, fit, speed and memory use) sets the ranking.	GGUF files (opens in a new tab)
`Q3_K_M`	22.2 GB	48.0 GB	84.6 tok/s	Runs great	68Good quality (B) · 68 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 81/100 (quality, fit, speed and memory use) sets the ranking.	GGUF files (opens in a new tab)
`Q4_K_M`	26.2 GB	48.0 GB	69.2 tok/s	Runs great	77Great quality (A) · 77 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 87/100 (quality, fit, speed and memory use) sets the ranking.	GGUF (opens in a new tab)
`Q5_K_M`	29.5 GB	48.0 GB	59.1 tok/s	Runs great	79Great quality (A) · 79 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 89/100 (quality, fit, speed and memory use) sets the ranking.	GGUF files (opens in a new tab)
`Q6_K`	33.2 GB	48.0 GB	51.1 tok/s	Runs great	81Great quality (A) · 81 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 91/100 (quality, fit, speed and memory use) sets the ranking.	GGUF files (opens in a new tab)
`Q8_0`	41.2 GB	48.0 GB	39.1 tok/s	Runs welltight fit	82Great quality (A) · 82 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 90/100 (quality, fit, speed and memory use) sets the ranking.	GGUF files (opens in a new tab)
`F16`	72.7 GB	48.0 GB	—	Won't run	82Great quality (A) · 82 of 100: how capable the model is at F16, whatever it runs on. Match score 11/100 (quality, fit, speed and memory use) sets the ranking.	GGUF (opens in a new tab) Original weights (opens in a new tab)

Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.

Other hardware that runs it

82Great quality (A) · 82 of 100: how capable the model is at F16, whatever it runs on. Match score 91/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA RTX PRO 6000 Blackwell F16 · 98.2 tok/s · Runs great
81Great quality (A) · 81 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 91/100 (quality, fit, speed and memory use) sets the ranking. Apple M1 Max (64 GB) Q6_K · 72.3 tok/s · Runs great
81Great quality (A) · 81 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 91/100 (quality, fit, speed and memory use) sets the ranking. Apple M4 Max (64 GB) Q6_K · 90.1 tok/s · Runs great
79Great quality (A) · 79 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 90/100 (quality, fit, speed and memory use) sets the ranking. Apple M4 Pro (48 GB) Q5_K_M · 62.2 tok/s · Runs great
81Great quality (A) · 81 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 90/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA GeForce RTX 5090 Q6_K · 179 tok/s · Runs well (tight fit)
82Great quality (A) · 82 of 100: how capable the model is at F16, whatever it runs on. Match score 89/100 (quality, fit, speed and memory use) sets the ranking. Apple M2 Ultra (192 GB) F16 · 51.3 tok/s · Runs great

Quick answers

How much memory does Laguna XS 2.1 (33B-A3B) need on the AMD Ryzen AI Max 385 64GB?

At Q6_K it needs about 33.2 GB. The AMD Ryzen AI Max 385 64GB has 48.0 GB usable.

How fast is Laguna XS 2.1 (33B-A3B) on the AMD Ryzen AI Max 385 64GB?

About 51.1 tok/s at Q6_K, an estimate from the hardware’s memory bandwidth and the size of the model.

Which quantization of Laguna XS 2.1 (33B-A3B) should I use on the AMD Ryzen AI Max 385 64GB?

Q6_K. Of the versions that fit, it is the one that runs best; when two run equally well, the check prefers the higher-rated one.

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.