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Can the AMD Ryzen 5 PRO 8640U NAS (16 GB) run Mistral Large 4 (1T-A52B)?

67Good quality (B) · 67 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking.

No, it doesn’t fit

No. Mistral Large 4 (1T-A52B) needs about 423 GB even at Q2_K; the AMD Ryzen 5 PRO 8640U NAS (16 GB) has 12.0 GB usable.

Download Mistral Large 4 (1T-A52B)

Recommended: Q2_K. Every other quantization has its own download link in the table below.

Ollama

Ollama offers this only as a cloud model (it runs on Ollama’s servers, not your machine). To run it locally, use the GGUF files below.

Quantized files · GGUF

Works in LM Studio, llama.cpp, Jan and Ollama. No sign-in needed.

Download the Q2_K (UD-Q2_K_XL) files (opens in a new tab)

huggingface.co/unsloth/Mistral-Large-4-1T-A52B-GGUF (opens in a new tab)

ollama run hf.co/unsloth/Mistral-Large-4-1T-A52B-GGUF

Original weights · Hugging Face

Full-precision files from Mistral AI, for fine-tuning, vLLM, Transformers.

huggingface.co/mistralai/Mistral-Large-4-1T-A52B (opens in a new tab)

No sign-in needed.

Links checked 3 days ago against Hugging Face, Ollama and GitHub.

How it’s rated

Quality 67Good quality (B) · 67 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking.
How capable the model itself is at Q2_K, from its editorial quality tier scaled by the quantization or precision. It’s the same on any hardware that runs this variant. Scale: A+ 85+ · A 70+ · B 55+ · C 40+ · D under 40.
Runs Won't run
How well it runs on the AMD Ryzen 5 PRO 8640U NAS (16 GB): speed, capped by how well it fits in memory. Runs great: 30+ tokens/s (or near the image, video or decision speed target) · Runs well: 10+ tokens/s · Slow: 3+ tokens/s · Very slow: under 3 · Won’t run: doesn’t fit even with offload. A tight fit or RAM offload caps it at Runs well; heavy offload caps it at Slow.

Match score

To order lists, each result also gets a match score out of 100 from four parts. It favors the most capable model that still runs well.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.9.1 / 45
Memory fitFull marks when the model fits in the share of the NAS’s memory that models can use (the rest stays with the NAS system and its storage services); fewer when it goes past that limit.0.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.0.0 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.0.0 / 15
Match score9.1 / 100

The match score orders results; it is not shown as a grade. Quality and Runs are the two ratings in the tables.

It doesn’t fit, so only a reduced share of the quality points counts and fit, speed and memory use score zero.

Every quantization on the AMD Ryzen 5 PRO 8640U NAS (16 GB)

Quant Memory needed Available Speed Runs Quality Download
Q2_K 423 GB 12.0 GB — Won't run 67Good quality (B) · 67 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking. GGUF (UD-Q2_K_XL) · folder (opens in a new tab)
Q3_K_M 518 GB 12.0 GB — Won't run 81Great quality (A) · 81 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 10/100 (quality, fit, speed and memory use) sets the ranking. GGUF (UD-Q3_K_XL) · folder (opens in a new tab)
Q4_K_M 645 GB 12.0 GB — Won't run 91Excellent quality (A+) · 91 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 12/100 (quality, fit, speed and memory use) sets the ranking. GGUF (UD-Q4_K_XL) · folder (opens in a new tab)
Q5_K_M 750 GB 12.0 GB — Won't run 93Excellent quality (A+) · 93 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 12/100 (quality, fit, speed and memory use) sets the ranking. GGUF (UD-Q5_K_XL) · folder (opens in a new tab)
Q6_K 866 GB 12.0 GB — Won't run 95Excellent quality (A+) · 95 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 12/100 (quality, fit, speed and memory use) sets the ranking. GGUF (UD-Q6_K_XL) · folder (opens in a new tab)
Q8_0 1,119 GB 12.0 GB — Won't run 96Excellent quality (A+) · 96 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 13/100 (quality, fit, speed and memory use) sets the ranking. GGUF (opens in a new tab)
F16 2,109 GB 12.0 GB — Won't run 96Excellent quality (A+) · 96 of 100: how capable the model is at F16, whatever it runs on. Match score 13/100 (quality, fit, speed and memory use) sets the ranking. GGUF · folder (opens in a new tab) Original weights (opens in a new tab)

Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.

Hardware that can run it

Models that do run on the AMD Ryzen 5 PRO 8640U NAS (16 GB)

Quick answers

How much memory does Mistral Large 4 (1T-A52B) need on the AMD Ryzen 5 PRO 8640U NAS 16GB?

Even at Q2_K it needs about 423 GB; the AMD Ryzen 5 PRO 8640U NAS 16GB has 12.0 GB usable.

What can the AMD Ryzen 5 PRO 8640U NAS 16GB run instead?

Mellum2.1 Thinking (12B-A2.5B), Gemma 4 12B and Maple Preview (20B-A1B) run best on it; the page lists more, each with its speed.

What hardware can run Mistral Large 4 (1T-A52B)?

M3 Ultra 512GB, AMD EPYC 7002 / 7003 series NAS 512GB and M5 Ultra 512GB run it; the page lists more, each with its speed.

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.

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