Nex N2.6 (321B-A18B) on AMD Ryzen AI Max+ 395 (64 GB)

Can the AMD Ryzen AI Max+ 395 (64 GB) run Nex N2.6 (321B-A18B)?

No, it doesn’t fit

No. Nex N2.6 (321B-A18B) needs about 133 GB even at Q2_K; the AMD Ryzen AI Max+ 395 (64 GB) has 48.0 GB usable.

Download Nex N2.6 (321B-A18B)

Recommended: Q2_K. Every other quantization has its own download link in the table below.

Quantized files · GGUF

Works in LM Studio, llama.cpp, Jan and Ollama. No sign-in needed.

Download the Q2_K files (opens in a new tab)

huggingface.co/bartowski/Nex-N2.6-GGUF (opens in a new tab)

ollama run hf.co/bartowski/Nex-N2.6-GGUF

Original weights · Hugging Face

Full-precision files from Nex-AGI, for fine-tuning, vLLM, Transformers.

huggingface.co/nex-agi/Nex-N2.6 (opens in a new tab)

No sign-in needed.

Links checked 7 hours ago against Hugging Face, Ollama and GitHub.

How it’s rated

Quality 67Good quality (B) · 67 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking.: How capable the model itself is at Q2_K, from its editorial quality tier scaled by the quantization or precision. It’s the same on any hardware that runs this variant. Scale: A+ 85+ · A 70+ · B 55+ · C 40+ · D under 40.
Runs Won't run: How well it runs on the AMD Ryzen AI Max+ 395 (64 GB): speed, capped by how well it fits in memory. Runs great: 30+ tokens/s (or near the image, video or decision speed target) · Runs well: 10+ tokens/s · Slow: 3+ tokens/s · Very slow: under 3 · Won’t run: doesn’t fit even with offload. A tight fit or RAM offload caps it at Runs well; heavy offload caps it at Slow.

Match score

To order lists, each result also gets a match score out of 100 from four parts. It favors the most capable model that still runs well.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.	9.2 / 45
Memory fitFull marks when the model fits in the share of unified memory the GPU can use; fewer when it goes past that limit.	0.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.	0.0 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.	0.0 / 15
Match score	9.2 / 100

The match score orders results; it is not shown as a grade. Quality and Runs are the two ratings in the tables.

It doesn’t fit, so only a reduced share of the quality points counts and fit, speed and memory use score zero.

Every quantization on the AMD Ryzen AI Max+ 395 (64 GB)

Quant	Memory needed	Available	Speed	Runs	Quality	Download
`Q2_K`	133 GB	48.0 GB	—	Won't run	67Good quality (B) · 67 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 9/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · folder (opens in a new tab)
`Q3_K_M`	162 GB	48.0 GB	—	Won't run	81Great quality (A) · 81 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 10/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · folder (opens in a new tab)
`Q4_K_M`	201 GB	48.0 GB	—	Won't run	92Excellent quality (A+) · 92 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 12/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · folder (opens in a new tab)
`Q5_K_M`	233 GB	48.0 GB	—	Won't run	94Excellent quality (A+) · 94 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 12/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · folder (opens in a new tab)
`Q6_K`	268 GB	48.0 GB	—	Won't run	96Excellent quality (A+) · 96 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 12/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · folder (opens in a new tab)
`Q8_0`	345 GB	48.0 GB	—	Won't run	97Excellent quality (A+) · 97 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 13/100 (quality, fit, speed and memory use) sets the ranking.	GGUF · folder (opens in a new tab)
`F16`	647 GB	48.0 GB	—	Won't run	97Excellent quality (A+) · 97 of 100: how capable the model is at F16, whatever it runs on. Match score 13/100 (quality, fit, speed and memory use) sets the ranking.	Original weights (opens in a new tab)

Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.

Hardware that can run it

92Excellent quality (A+) · 92 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 95/100 (quality, fit, speed and memory use) sets the ranking. Apple M3 Ultra (512 GB) Q4_K_M · 41.4 tok/s · Runs great
81Great quality (A) · 81 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 90/100 (quality, fit, speed and memory use) sets the ranking. Apple M3 Ultra (256 GB) Q3_K_M · 51.7 tok/s · Runs well (tight fit)
67Good quality (B) · 67 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 84/100 (quality, fit, speed and memory use) sets the ranking. Apple M2 Ultra (192 GB) Q2_K · 62.2 tok/s · Runs well (tight fit)
96Excellent quality (A+) · 96 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 98/100 (quality, fit, speed and memory use) sets the ranking. Apple M5 Ultra (512 GB) Q6_K · 41.6 tok/s · Runs great
94Excellent quality (A+) · 94 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 97/100 (quality, fit, speed and memory use) sets the ranking. AMD Instinct MI350X Q5_K_M · 165 tok/s · Runs great
92Excellent quality (A+) · 92 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 96/100 (quality, fit, speed and memory use) sets the ranking. AMD Instinct MI325X Q4_K_M · 161 tok/s · Runs great

Models that do run on the AMD Ryzen AI Max+ 395 (64 GB)

92Excellent quality (A+) · 92 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 96/100 (quality, fit, speed and memory use) sets the ranking. Qwen3.6 35B-A3B Q6_K · 51.1 tok/s
92Excellent quality (A+) · 92 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 96/100 (quality, fit, speed and memory use) sets the ranking. MiniCPM-V 4.7 35B-A3B Q6_K · 51.1 tok/s
92Excellent quality (A+) · 92 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 96/100 (quality, fit, speed and memory use) sets the ranking. Qwen3.5 35B-A3B Q6_K · 51.1 tok/s
91Excellent quality (A+) · 91 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 95/100 (quality, fit, speed and memory use) sets the ranking. Nex N2 Mini (35B-A3B) Q6_K · 51.1 tok/s
90Excellent quality (A+) · 90 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 95/100 (quality, fit, speed and memory use) sets the ranking. KAT-Coder V2.5 Dev (35B-A3B) Q6_K · 51.1 tok/s

Quick answers

How much memory does Nex N2.6 (321B-A18B) need on the AMD Ryzen AI Max+ 395 64GB?

Even at Q2_K it needs about 133 GB; the AMD Ryzen AI Max+ 395 64GB has 48.0 GB usable.

What can the AMD Ryzen AI Max+ 395 64GB run instead?

Qwen3.6 35B-A3B, MiniCPM-V 4.7 35B-A3B and Qwen3.5 35B-A3B run best on it; the page lists more, each with its speed.

What hardware can run Nex N2.6 (321B-A18B)?

M3 Ultra 512GB, M3 Ultra 256GB and M2 Ultra 192GB run it; the page lists more, each with its speed.

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.