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Can the NVIDIA GeForce RTX 4090 run Nous Hermes 2 Mixtral 8x7B DPO?

36Basic quality (D) · 36 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 70/100 (quality, fit, speed and memory use) sets the ranking.

Yes, it runs well (tight fit)

Runs well (tight fit). At Q2_K it needs about 21.6 GB of 24.0 GB usable, with an estimated speed of 106 tok/s.

Best quant
Q2_K
Generation speed
106 tok/s
Prompt processing
4,610 tok/s
First token (1K prompt)
0.3 s
Largest safe context
26K

Best app to run it on the NVIDIA GeForce RTX 4090

On Windows

Ollama

Command line + local API · runs on llama.cpp (ggml), MLX (Apple silicon, preview)

  • One command with Ollama’s own build of this model.
  • Serves an OpenAI-compatible API that other apps and coding tools can use.
ollama run nous-hermes2-mixtral:8x7b-dpo-q2_K
  • LM Studio Point-and-click: search, download and chat in one window.
  • llama.cpp Usually the first to support new model architectures.

On Linux

Ollama

Command line + local API · runs on llama.cpp (ggml), MLX (Apple silicon, preview)

  • One command with Ollama’s own build of this model.
  • Serves an OpenAI-compatible API that other apps and coding tools can use.
ollama run nous-hermes2-mixtral:8x7b-dpo-q2_K
  • LM Studio Point-and-click: search, download and chat in one window.
  • llama.cpp Usually the first to support new model architectures.

How we choose: the files published for this model, your operating system and GPU, whether it fits fully in memory, and published speed tests (MLX vs llama.cpp on Apple silicon, vLLM vs llama.cpp vs Ollama on NVIDIA). Details.

Download Nous Hermes 2 Mixtral 8x7B DPO

Recommended for the NVIDIA GeForce RTX 4090: Q2_K. Every other quantization has its own download link in the table below.

Quickest · Ollama

One command downloads a ready-to-run version and starts a chat.

Get Ollama at ollama.com/download (opens in a new tab) · model page (opens in a new tab)

ollama run nous-hermes2-mixtral:8x7b-dpo-q2_K

Quantized files · GGUF

Works in LM Studio, llama.cpp, Jan and Ollama. No sign-in needed.

Download the Q2_K file (opens in a new tab)

huggingface.co/NousResearch/Nous-Hermes-2-Mixtral-8x7B-DPO-GGUF (opens in a new tab)

ollama run hf.co/NousResearch/Nous-Hermes-2-Mixtral-8x7B-DPO-GGUF:Q2_K

Original weights · Hugging Face

Full-precision files from Nous Research, for fine-tuning, vLLM, Transformers.

huggingface.co/NousResearch/Nous-Hermes-2-Mixtral-8x7B-DPO (opens in a new tab)

No sign-in needed.

Links checked 3 days ago against Hugging Face, Ollama and GitHub.

How it’s rated

Quality 36Basic quality (D) · 36 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 70/100 (quality, fit, speed and memory use) sets the ranking.
How capable the model itself is at Q2_K, from its editorial quality tier scaled by the quantization or precision. It’s the same on any hardware that runs this variant. Scale: A+ 85+ · A 70+ · B 55+ · C 40+ · D under 40.
Runs Runs welltight fit
How well it runs on the NVIDIA GeForce RTX 4090: speed, capped by how well it fits in memory. Runs great: 30+ tokens/s (or near the image, video or decision speed target) · Runs well: 10+ tokens/s · Slow: 3+ tokens/s · Very slow: under 3 · Won’t run: doesn’t fit even with offload. A tight fit or RAM offload caps it at Runs well; heavy offload caps it at Slow.

Match score

To order lists, each result also gets a match score out of 100 from four parts. It favors the most capable model that still runs well.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.16.4 / 45
Memory fitFull marks when everything sits in GPU memory; fewer when part spills to system RAM.24.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.15.0 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.15.0 / 15
Match score70.4 / 100

The match score orders results; it is not shown as a grade. Quality and Runs are the two ratings in the tables.

Every quantization on the NVIDIA GeForce RTX 4090

Quant Memory needed Available Speed Runs Quality Download
Q2_K 21.6 GB 24.0 GB 106 tok/s Runs welltight fit 36Basic quality (D) · 36 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 70/100 (quality, fit, speed and memory use) sets the ranking. GGUF (opens in a new tab)
Q3_K_M 25.8 GB 24.0 GB 49.9 tok/s Runs welloffloads to RAM 43Fair quality (C) · 43 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 59/100 (quality, fit, speed and memory use) sets the ranking. GGUF (opens in a new tab)
Q4_K_M 31.4 GB 24.0 GB 19.3 tok/s Runs welloffloads to RAM 49Fair quality (C) · 49 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 57/100 (quality, fit, speed and memory use) sets the ranking. GGUF (opens in a new tab)
Q5_K_M 36.0 GB 24.0 GB 12.4 tok/s Slowheavy RAM offload 50Fair quality (C) · 50 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 50/100 (quality, fit, speed and memory use) sets the ranking. GGUF (opens in a new tab)
Q6_K 41.2 GB 24.0 GB 8.8 tok/s Slowheavy RAM offload 51Fair quality (C) · 51 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 49/100 (quality, fit, speed and memory use) sets the ranking. GGUF (opens in a new tab)
Q8_0 52.4 GB 24.0 GB — Won't run 52Fair quality (C) · 52 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 7/100 (quality, fit, speed and memory use) sets the ranking. GGUF (opens in a new tab)
F16 96.3 GB 24.0 GB — Won't run 52Fair quality (C) · 52 of 100: how capable the model is at F16, whatever it runs on. Match score 7/100 (quality, fit, speed and memory use) sets the ranking. Original weights (opens in a new tab)

Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.

Other hardware that runs it

Quick answers

How much memory does Nous Hermes 2 Mixtral 8x7B DPO need on the RTX 4090 24GB?

At Q2_K it needs about 21.6 GB. The RTX 4090 24GB has 24.0 GB usable.

How fast is Nous Hermes 2 Mixtral 8x7B DPO on the RTX 4090 24GB?

About 106 tok/s at Q2_K, an estimate from the hardware’s memory bandwidth and the size of the model.

Which quantization of Nous Hermes 2 Mixtral 8x7B DPO should I use on the RTX 4090 24GB?

Q2_K. Of the versions that fit, it is the one that runs best; when two run equally well, the check prefers the higher-rated one.

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.

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