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Can the AMD Ryzen AI Max+ 395 (128 GB) run Pixtral Large 124B (2411)?

54Fair quality (C) · 54 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 68/100 (quality, fit, speed and memory use) sets the ranking.

Yes, but slowly

Slow. At Q2_K it needs about 60.8 GB of 96.0 GB usable, with an estimated speed of 3.6 tok/s.

Best quant
Q2_K
Generation speed
3.6 tok/s
Prompt processing
297 tok/s
First token (1K prompt)
3.4 s
Largest safe context
103K

Best app to run it on the AMD Ryzen AI Max+ 395 (128 GB)

On Windows

Docker Model Runner

Command line + local API · runs on llama.cpp, vLLM

  • Handy if you already work in Docker.
docker model run hf.co/mistralai/Pixtral-Large-Instruct-2411

On Linux

Docker Model Runner

Command line + local API · runs on llama.cpp, vLLM

  • Handy if you already work in Docker.
docker model run hf.co/mistralai/Pixtral-Large-Instruct-2411

How we choose: the files published for this model, your operating system and GPU, whether it fits fully in memory, and published speed tests (MLX vs llama.cpp on Apple silicon, vLLM vs llama.cpp vs Ollama on NVIDIA). Details.

Download Pixtral Large 124B (2411)

Original weights · Hugging Face

Full-precision files from Mistral AI, for fine-tuning, vLLM, Transformers.

huggingface.co/mistralai/Pixtral-Large-Instruct-2411 (opens in a new tab)

No sign-in needed.

Links checked 3 days ago against Hugging Face, Ollama and GitHub.

How it’s rated

Quality 54Fair quality (C) · 54 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 68/100 (quality, fit, speed and memory use) sets the ranking.
How capable the model itself is at Q2_K, from its editorial quality tier scaled by the quantization or precision. It’s the same on any hardware that runs this variant. Scale: A+ 85+ · A 70+ · B 55+ · C 40+ · D under 40.
Runs Slow
How well it runs on the AMD Ryzen AI Max+ 395 (128 GB): speed, capped by how well it fits in memory. Runs great: 30+ tokens/s (or near the image, video or decision speed target) · Runs well: 10+ tokens/s · Slow: 3+ tokens/s · Very slow: under 3 · Won’t run: doesn’t fit even with offload. A tight fit or RAM offload caps it at Runs well; heavy offload caps it at Slow.

Match score

To order lists, each result also gets a match score out of 100 from four parts. It favors the most capable model that still runs well.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.24.6 / 45
Memory fitFull marks when the model fits in the share of unified memory the GPU can use; fewer when it goes past that limit.25.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.4.5 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.14.6 / 15
Match score68.7 / 100

The match score orders results; it is not shown as a grade. Quality and Runs are the two ratings in the tables.

Every quantization on the AMD Ryzen AI Max+ 395 (128 GB)

Quant Memory needed Available Speed Runs Quality Download
Q2_K 60.8 GB 96.0 GB 3.6 tok/s Slow 54Fair quality (C) · 54 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 68/100 (quality, fit, speed and memory use) sets the ranking. All files (opens in a new tab)
Q3_K_M 72.0 GB 96.0 GB 2.8 tok/s Very slow 65Good quality (B) · 65 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 73/100 (quality, fit, speed and memory use) sets the ranking. All files (opens in a new tab)
Q4_K_M 86.9 GB 96.0 GB 2.2 tok/s Very slowtight fit 74Great quality (A) · 74 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 75/100 (quality, fit, speed and memory use) sets the ranking. All files (opens in a new tab)
Q5_K_M 99.3 GB 96.0 GB 1.5 tok/s Very slowover GPU memory limit 75Great quality (A) · 75 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 61/100 (quality, fit, speed and memory use) sets the ranking. All files (opens in a new tab)
Q6_K 113 GB 96.0 GB 1.3 tok/s Very slowfar over GPU memory limit 77Great quality (A) · 77 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 56/100 (quality, fit, speed and memory use) sets the ranking. All files (opens in a new tab)
Q8_0 143 GB 96.0 GB — Won't run 78Great quality (A) · 78 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 10/100 (quality, fit, speed and memory use) sets the ranking. All files (opens in a new tab)
F16 259 GB 96.0 GB — Won't run 78Great quality (A) · 78 of 100: how capable the model is at F16, whatever it runs on. Match score 10/100 (quality, fit, speed and memory use) sets the ranking. Original weights (opens in a new tab)

Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.

Other hardware that runs it

Quick answers

How much memory does Pixtral Large 124B (2411) need on the AMD Ryzen AI Max+ 395 128GB?

At Q2_K it needs about 60.8 GB. The AMD Ryzen AI Max+ 395 128GB has 96.0 GB usable.

How fast is Pixtral Large 124B (2411) on the AMD Ryzen AI Max+ 395 128GB?

About 3.6 tok/s at Q2_K, an estimate from the hardware’s memory bandwidth and the size of the model.

Which quantization of Pixtral Large 124B (2411) should I use on the AMD Ryzen AI Max+ 395 128GB?

Q2_K. Of the versions that fit, it is the one that runs best; when two run equally well, the check prefers the higher-rated one.

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.

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