Qwen3 Next 80B-A3B Instruct on NVIDIA GB10 (64 GB)

Can the NVIDIA GB10 (64 GB) run Qwen3 Next 80B-A3B Instruct?

Yes, it runs well (tight fit)

Runs well (tight fit). At Q4_K_M it needs about 55.0 GB of 57.6 GB usable, with an estimated speed of 81.2 tok/s.

Best quant: Q4_K_M
Generation speed: 81.2 tok/s
Prompt processing: 7,440 tok/s
First token (1K prompt): 0.3 s
Largest safe context: 110K

Best app to run it on the NVIDIA GB10 (64 GB)

On Linux

Ollama

Command line + local API · runs on llama.cpp (ggml), MLX (Apple silicon, preview)

One command with Ollama’s own build of this model.
Serves an OpenAI-compatible API that other apps and coding tools can use.

ollama run qwen3-next:80b-a3b-instruct-q4_K_M

LM Studio Point-and-click: search, download and chat in one window.
llama.cpp Usually the first to support new model architectures.

Want an agent? Qwen3 Next 80B-A3B Instruct supports tool use, so you can pair a llama.cpp or MLX LM server with one of these. Apps that run on this computer come first.

Coding agents

Personal assistants

How we choose: the files published for this model, your operating system and GPU, whether it fits fully in memory, and published speed tests (MLX vs llama.cpp on Apple silicon, vLLM vs llama.cpp vs Ollama on NVIDIA). Details.

Download Qwen3 Next 80B-A3B Instruct

Recommended for the NVIDIA GB10 (64 GB): Q4_K_M. Every other quantization has its own download link in the table below.

Quickest · Ollama

One command downloads a ready-to-run version and starts a chat.

Get Ollama at ollama.com/download (opens in a new tab) · model page (opens in a new tab)

ollama run qwen3-next:80b-a3b-instruct-q4_K_M

Quantized files · GGUF

Works in LM Studio, llama.cpp, Jan and Ollama. No sign-in needed.

Download the Q4_K_M file (opens in a new tab)

huggingface.co/Qwen/Qwen3-Next-80B-A3B-Instruct-GGUF (opens in a new tab)

ollama run hf.co/Qwen/Qwen3-Next-80B-A3B-Instruct-GGUF:Q4_K_M

Original weights · Hugging Face

Full-precision files from Alibaba, for fine-tuning, vLLM, Transformers.

huggingface.co/Qwen/Qwen3-Next-80B-A3B-Instruct (opens in a new tab)

No sign-in needed.

Official repo · GitHub

Reference code, inference scripts and docs from Alibaba. The weights themselves download from Hugging Face.

github.com/QwenLM/Qwen3 (opens in a new tab)

Qwen’s main repo, renamed from Qwen2.5 to Qwen3; it still documents Qwen2.5.

git clone https://github.com/QwenLM/Qwen3

Links checked 3 days ago against Hugging Face, Ollama and GitHub.

How it’s rated

Quality 79Great quality (A) · 79 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 89/100 (quality, fit, speed and memory use) sets the ranking.: How capable the model itself is at Q4_K_M, from its editorial quality tier scaled by the quantization or precision. It’s the same on any hardware that runs this variant. Scale: A+ 85+ · A 70+ · B 55+ · C 40+ · D under 40.
Runs Runs welltight fit: How well it runs on the NVIDIA GB10 (64 GB): speed, capped by how well it fits in memory. Runs great: 30+ tokens/s (or near the image, video or decision speed target) · Runs well: 10+ tokens/s · Slow: 3+ tokens/s · Very slow: under 3 · Won’t run: doesn’t fit even with offload. A tight fit or RAM offload caps it at Runs well; heavy offload caps it at Slow.

Match score

To order lists, each result also gets a match score out of 100 from four parts. It favors the most capable model that still runs well.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.	35.9 / 45
Memory fitFull marks when the model fits in the share of unified memory the GPU can use; fewer when it goes past that limit.	24.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.	15.0 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.	15.0 / 15
Match score	89.9 / 100

The match score orders results; it is not shown as a grade. Quality and Runs are the two ratings in the tables.

Every quantization on the NVIDIA GB10 (64 GB)

Quant	Memory needed	Available	Speed	Runs	Quality	Download
`Q2_K`	37.9 GB	57.6 GB	117 tok/s	Runs great	58Good quality (B) · 58 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 81/100 (quality, fit, speed and memory use) sets the ranking.	GGUF files (opens in a new tab)
`Q3_K_M`	45.3 GB	57.6 GB	98.4 tok/s	Runs great	70Great quality (A) · 70 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 86/100 (quality, fit, speed and memory use) sets the ranking.	GGUF files (opens in a new tab)
`Q4_K_M`	55.0 GB	57.6 GB	81.2 tok/s	Runs welltight fit	79Great quality (A) · 79 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 89/100 (quality, fit, speed and memory use) sets the ranking.	GGUF (opens in a new tab)
`Q5_K_M`	63.1 GB	57.6 GB	—	Won't run	81Great quality (A) · 81 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 10/100 (quality, fit, speed and memory use) sets the ranking.	GGUF (opens in a new tab)
`Q6_K`	72.1 GB	57.6 GB	—	Won't run	83Great quality (A) · 83 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 11/100 (quality, fit, speed and memory use) sets the ranking.	GGUF (opens in a new tab)
`Q8_0`	91.6 GB	57.6 GB	—	Won't run	84Great quality (A) · 84 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 11/100 (quality, fit, speed and memory use) sets the ranking.	GGUF (opens in a new tab)
`F16`	168 GB	57.6 GB	—	Won't run	84Great quality (A) · 84 of 100: how capable the model is at F16, whatever it runs on. Match score 11/100 (quality, fit, speed and memory use) sets the ranking.	Original weights (opens in a new tab)

Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.

Other hardware that runs it

84Great quality (A) · 84 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 92/100 (quality, fit, speed and memory use) sets the ranking. Apple M2 Ultra (192 GB) Q8_0 · 92.8 tok/s · Runs great
84Great quality (A) · 84 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 92/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA GB10 (128 GB) Q8_0 · 46.8 tok/s · Runs great
83Great quality (A) · 83 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 92/100 (quality, fit, speed and memory use) sets the ranking. AMD Ryzen AI Max+ 395 (128 GB) Q6_K · 51.1 tok/s · Runs great
83Great quality (A) · 83 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 92/100 (quality, fit, speed and memory use) sets the ranking. Apple M4 Max (128 GB) Q6_K · 90.1 tok/s · Runs great
83Great quality (A) · 83 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 92/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA RTX PRO 6000 Blackwell Q6_K · 179 tok/s · Runs great
83Great quality (A) · 83 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 92/100 (quality, fit, speed and memory use) sets the ranking. NVIDIA RTX Spark N1X (6144-core GPU) (128 GB) Q6_K · 65.1 tok/s · Runs great

Quick answers

How much memory does Qwen3 Next 80B-A3B Instruct need on the NVIDIA GB10 64GB?

At Q4_K_M it needs about 55.0 GB. The NVIDIA GB10 64GB has 57.6 GB usable.

How fast is Qwen3 Next 80B-A3B Instruct on the NVIDIA GB10 64GB?

About 81.2 tok/s at Q4_K_M, an estimate from the hardware’s memory bandwidth and the size of the model.

Which quantization of Qwen3 Next 80B-A3B Instruct should I use on the NVIDIA GB10 64GB?

Q4_K_M. Of the versions that fit, it is the one that runs best; when two run equally well, the check prefers the higher-rated one.

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.