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Can the AMD Ryzen AI 9 HX 370 (DDR5 SO-DIMM) (64 GB) run Qwen3.5 122B-A10B?

64Good quality (B) · 64 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 56/100 (quality, fit, speed and memory use) sets the ranking.

Yes, but slowly (far over GPU memory limit)

Slow (far over GPU memory limit). At Q2_K it needs about 54.7 GB of 48.0 GB usable, with an estimated speed of 12.6 tok/s.

Best quant
Q2_K
Generation speed
12.6 tok/s
Prompt processing
1,476 tok/s
First token (1K prompt)
0.7 s
Largest safe context
—

Best app to run it on the AMD Ryzen AI 9 HX 370 (DDR5 SO-DIMM) (64 GB)

On Windows

Lemonade

Desktop app · runs on llama.cpp, ONNX Runtime GenAI (Ryzen AI NPU)

  • Splits the model between GPU memory and system RAM, which this setup needs.
  • Built for Ryzen AI and Strix Halo, including NPU + iGPU modes on Windows.
lemonade pull unsloth/Qwen3.5-122B-A10B-GGUF:UD-Q2_K_XL
  • llama.cpp Splits the model between GPU memory and system RAM, which this setup needs.
  • LM Studio Splits the model between GPU memory and system RAM, which this setup needs.

On Linux

Lemonade

Desktop app · runs on llama.cpp, ONNX Runtime GenAI (Ryzen AI NPU)

  • Splits the model between GPU memory and system RAM, which this setup needs.
  • Built for Ryzen AI and Strix Halo, including NPU + iGPU modes on Windows.
lemonade pull unsloth/Qwen3.5-122B-A10B-GGUF:UD-Q2_K_XL
  • llama.cpp Splits the model between GPU memory and system RAM, which this setup needs.
  • LM Studio Splits the model between GPU memory and system RAM, which this setup needs.

Want an agent? Qwen3.5 122B-A10B supports tool use, so you can pair a llama.cpp or MLX LM server with one of these. Apps that run on this computer come first.

Coding agents

Personal assistants

How we choose: the files published for this model, your operating system and GPU, whether it fits fully in memory, and published speed tests (MLX vs llama.cpp on Apple silicon, vLLM vs llama.cpp vs Ollama on NVIDIA). Details.

Download Qwen3.5 122B-A10B

Recommended for the AMD Ryzen AI 9 HX 370 (DDR5 SO-DIMM) (64 GB): Q2_K. Every other quantization has its own download link in the table below.

Quickest · Ollama

One command downloads a ready-to-run version and starts a chat.

Get Ollama at ollama.com/download (opens in a new tab) · model page (opens in a new tab)

ollama run qwen3.5:122b

Quantized files · GGUF

Works in LM Studio, llama.cpp, Jan and Ollama. No sign-in needed.

Download the Q2_K (UD-Q2_K_XL) file (opens in a new tab)

huggingface.co/unsloth/Qwen3.5-122B-A10B-GGUF (opens in a new tab)

ollama run hf.co/unsloth/Qwen3.5-122B-A10B-GGUF:UD-Q2_K_XL

Original weights · Hugging Face

Full-precision files from Alibaba, for fine-tuning, vLLM, Transformers.

huggingface.co/Qwen/Qwen3.5-122B-A10B (opens in a new tab)

No sign-in needed.

Official repo · GitHub

Reference code, inference scripts and docs from Alibaba. The weights themselves download from Hugging Face.

github.com/QwenLM/Qwen3.8 (opens in a new tab)

Qwen’s current repo: Qwen3.5 and Qwen3.6 redirect here.

git clone https://github.com/QwenLM/Qwen3.8

Links checked 3 days ago against Hugging Face, Ollama and GitHub.

How it’s rated

Quality 64Good quality (B) · 64 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 56/100 (quality, fit, speed and memory use) sets the ranking.
How capable the model itself is at Q2_K, from its editorial quality tier scaled by the quantization or precision. It’s the same on any hardware that runs this variant. Scale: A+ 85+ · A 70+ · B 55+ · C 40+ · D under 40.
Runs Slowfar over GPU memory limit
How well it runs on the AMD Ryzen AI 9 HX 370 (DDR5 SO-DIMM) (64 GB): speed, capped by how well it fits in memory. Runs great: 30+ tokens/s (or near the image, video or decision speed target) · Runs well: 10+ tokens/s · Slow: 3+ tokens/s · Very slow: under 3 · Won’t run: doesn’t fit even with offload. A tight fit or RAM offload caps it at Runs well; heavy offload caps it at Slow.

Match score

To order lists, each result also gets a match score out of 100 from four parts. It favors the most capable model that still runs well.

Model qualityEditorial quality tier of the model, scaled by the quantization or precision used.29.0 / 45
Memory fitFull marks when the model fits in the share of unified memory the GPU can use; fewer when it goes past that limit.4.0 / 25
SpeedGeneration speed against a 40 tokens/s target for LLMs, or render time against a target for image and video.8.4 / 15
Memory useRewards using the memory you have, so a bigger, better variant beats a tiny one that leaves most memory idle.15.0 / 15
Match score56.4 / 100

The match score orders results; it is not shown as a grade. Quality and Runs are the two ratings in the tables.

Every quantization on the AMD Ryzen AI 9 HX 370 (DDR5 SO-DIMM) (64 GB)

Quant Memory needed Available Speed Runs Quality Download
Q2_K 54.7 GB 48.0 GB 12.6 tok/s Slowfar over GPU memory limit 64Good quality (B) · 64 of 100: how capable the model is at Q2_K, whatever it runs on. Match score 56/100 (quality, fit, speed and memory use) sets the ranking. GGUF (UD-Q2_K_XL) (opens in a new tab)
Q3_K_M 65.9 GB 48.0 GB — Won't run 77Great quality (A) · 77 of 100: how capable the model is at Q3_K_M, whatever it runs on. Match score 10/100 (quality, fit, speed and memory use) sets the ranking. GGUF · folder (opens in a new tab)
Q4_K_M 80.9 GB 48.0 GB — Won't run 87Excellent quality (A+) · 87 of 100: how capable the model is at Q4_K_M, whatever it runs on. Match score 11/100 (quality, fit, speed and memory use) sets the ranking. GGUF · folder (opens in a new tab)
Q5_K_M 93.5 GB 48.0 GB — Won't run 89Excellent quality (A+) · 89 of 100: how capable the model is at Q5_K_M, whatever it runs on. Match score 12/100 (quality, fit, speed and memory use) sets the ranking. GGUF · folder (opens in a new tab)
Q6_K 107 GB 48.0 GB — Won't run 91Excellent quality (A+) · 91 of 100: how capable the model is at Q6_K, whatever it runs on. Match score 12/100 (quality, fit, speed and memory use) sets the ranking. GGUF · folder (opens in a new tab)
Q8_0 137 GB 48.0 GB — Won't run 92Excellent quality (A+) · 92 of 100: how capable the model is at Q8_0, whatever it runs on. Match score 12/100 (quality, fit, speed and memory use) sets the ranking. GGUF · folder (opens in a new tab)
F16 255 GB 48.0 GB — Won't run 92Excellent quality (A+) · 92 of 100: how capable the model is at F16, whatever it runs on. Match score 12/100 (quality, fit, speed and memory use) sets the ranking. GGUF · folder (opens in a new tab) Original weights (opens in a new tab)

Memory figures assume 8K of context. Longer conversations or documents grow the KV cache.

Other hardware that runs it

Quick answers

How much memory does Qwen3.5 122B-A10B need on the AMD Ryzen AI 9 HX 370 (DDR5 SO-DIMM) 64GB?

At Q2_K it needs about 54.7 GB. The AMD Ryzen AI 9 HX 370 (DDR5 SO-DIMM) 64GB has 48.0 GB usable.

How fast is Qwen3.5 122B-A10B on the AMD Ryzen AI 9 HX 370 (DDR5 SO-DIMM) 64GB?

About 12.6 tok/s at Q2_K, an estimate from the hardware’s memory bandwidth and the size of the model.

Which quantization of Qwen3.5 122B-A10B should I use on the AMD Ryzen AI 9 HX 370 (DDR5 SO-DIMM) 64GB?

Q2_K. Of the versions that fit, it is the one that runs best; when two run equally well, the check prefers the higher-rated one.

Estimates come from published hardware specs and our open formulas, not from running the model on your machine. Real speed varies with runtime, drivers and settings. Numbers marked “Measured” come from a linked benchmark.

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